Zhihong
GUO
郭志宏
PhD in Biological Chemistry
Associate Professor
Director of Glassblowing Facility
Research Area
Bioorganic chemistry and chemical biology. The effects of macromolecular crowding on the structure, function, and supramolecular organization of proteins
Bioorganic chemistry and chemical biology. Identification, characterization, catalytic mechanism, and organization of enzymes involved in the biosynthesis of menaquinone
Bioorganic chemistry and chemical biology. Development of drug leads inhibiting menaquinone biosynthesis as a means to combat microbial resistance
Bioorganic chemistry and chemical biology. The roles of 3a protein in the pathogenesis of the infections by severe acute respiratory syndrome (SARS) coronavirus. Postgraduate students in the research group receive extensive training in bioorganic chemist
Research Interests
Bioorganic chemistry
Biophysical chemistry
Biosynthesis of menaquinone
Chemical biology
Structural biology